Annalisa Pastore Selected Research

Alzheimer Disease (Alzheimer's Disease)

1/2020	Why does the Aβ peptide of Alzheimer share structural similarity with antimicrobial peptides?
1/2018	Glycation affects fibril formation of Aβ peptides.
1/2018	The role of oxidative stress in Friedreich's ataxia.
2/2016	Interplay of histidine residues of the Alzheimer's disease Aβ peptide governs its Zn-induced oligomerization.
10/2013	Real-time amyloid aggregation monitoring with a photonic crystal-based approach.
1/2013	Binding of methylene blue to a surface cleft inhibits the oligomerization and fibrillization of prion protein.
2/2012	Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease.
9/2011	A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease.
6/2008	EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers.
2/2003	From Alzheimer to Huntington: why is a structural understanding so difficult?

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Annalisa Pastore Research Topics

Disease

36	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 02/2002
23	Friedreich Ataxia (Friedreich's Ataxia) 12/2019 - 06/2004
13	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2015 - 05/2005
10	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 01/2021 - 08/2003
10	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 02/2003
7	Fragile X Syndrome (Martin Bell Syndrome) 04/2009 - 03/2003
4	Huntington Disease (Huntington's Disease) 01/2019 - 12/2008
4	Intellectual Disability (Idiocy) 06/2010 - 10/2003
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 12/2020
3	Neoplasms (Cancer) 01/2019 - 01/2013
3	Hemorrhage 01/2018 - 03/2011
3	Ataxia (Dyssynergia) 01/2017 - 01/2011
3	MYH9-Related Disorders 01/2013 - 12/2009
2	Thrombocytopenia (Thrombopenia) 01/2022 - 02/2014
2	Carcinogenesis 01/2019 - 10/2014
2	Infections 01/2018 - 05/2012
2	Bernard-Soulier Syndrome (Giant Platelet Syndrome) 09/2014 - 03/2011
2	Proteostasis Deficiencies 01/2013 - 06/2008
1	Frontotemporal Dementia (Semantic Dementia) 01/2022
1	TDP-43 Proteinopathies 12/2019
1	Bacterial Infections (Bacterial Infection) 12/2018
1	Tuberculosis (Tuberculoses) 01/2018
1	Congenital amegakaryocytic thrombocytopenia 01/2018
1	Bone Marrow Failure Disorders 01/2018
1	Stroke (Strokes) 10/2016
1	Pancreatitis 10/2016
1	Hypertension (High Blood Pressure) 10/2016
1	Type 2 Diabetes Mellitus (MODY) 05/2014
1	Coronary Artery Disease (Coronary Atherosclerosis) 05/2014
1	Iron Overload 08/2013
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2013
1	X-Linked Mental Retardation (Mental Retardation, X Linked) 04/2012
1	Meningitis 12/2011
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 10/2011
1	Neuroblastoma 10/2011
1	Renpenning syndrome 1 06/2010
1	Spinocerebellar Degenerations (Marinesco Sjogren Syndrome) 04/2010
1	Paraplegia (Spastic Paraplegia) 04/2010
1	familial dilated cardiomyopathy 04/2004
1	Brain Diseases (Brain Disorder) 02/2003
1	Cystic Fibrosis (Mucoviscidosis) 02/2003

Drug/Important Bio-Agent (IBA)

41	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2003
24	FrataxinIBA 12/2019 - 06/2004
21	polyglutamineIBA 01/2021 - 02/2002
14	Ataxin-3IBA 01/2021 - 08/2003
10	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2018 - 08/2004
9	Ataxin-1IBA 10/2014 - 05/2005
7	IronIBA 01/2019 - 09/2006
6	UbiquitinIBA 01/2021 - 12/2006
6	Peptides (Polypeptides)IBA 01/2020 - 02/2003
4	SulfurIBA 01/2019 - 08/2013
4	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2015 - 12/2006
4	Fragile X Mental Retardation ProteinIBA 04/2009 - 10/2003
3	PrionsIBA 12/2020 - 02/2003
3	RNA (Ribonucleic Acid)IBA 12/2020 - 03/2003
3	Amyloid (Amyloid Fibrils)IBA 01/2018 - 06/2008
3	Cysteine Proteases (Cysteine Protease)IBA 01/2015 - 12/2009
3	Amyloid beta-PeptidesIBA 10/2013 - 06/2008
3	Nonmuscle Myosin Type IIAIBA 01/2013 - 12/2009
3	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2006 - 07/2003
2	von Willebrand FactorIBA 09/2014 - 03/2011
2	Pharmaceutical PreparationsIBA 01/2013 - 01/2013
2	VaccinesIBA 12/2011 - 08/2002
2	Prion ProteinsIBA 10/2011 - 07/2010
1	EnzymesIBA 01/2022
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2022
1	Adenosine Diphosphate (ADP)IBA 01/2022
1	Huntingtin ProteinIBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2018
1	Thrombopoietin (c-mpl Ligand)IBA 01/2018
1	4,5,6,7- tetrahydroisoxazolo(4,5- c)pyridin- 3- ol (THPO)IBA 01/2018
1	Free RadicalsIBA 01/2018
1	romiplostim FDA Link 01/2018
1	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 10/2016
1	Histidine (L-Histidine)FDA Link 02/2016
1	Glutamine (L-Glutamine)FDA Link 05/2014
1	Arginine (L-Arginine)FDA Link 05/2014
1	Protein Isoforms (Isoforms)IBA 02/2014
1	Cytochromes c (Cytochrome c)IBA 02/2014
1	MetalsIBA 01/2014
1	Carrier Proteins (Binding Protein)IBA 01/2014
1	Methylene Blue (Methylthioninium Chloride)FDA Link 01/2013
1	Deubiquitinating EnzymesIBA 01/2013
1	SteroidsIBA 05/2012
1	Sulfates (Sulfates, Inorganic)IBA 05/2012
1	Serine (L-Serine)FDA Link 01/2012
1	AntigensIBA 12/2011
1	Endopeptidase K (Proteinase K)IBA 10/2011
1	poly-d-lysineIBA 10/2011
1	Biological ProductsIBA 09/2011
1	RNA Precursors (Precursor, mRNA)IBA 06/2010
1	ProteomeIBA 04/2010
1	Peptide Hydrolases (Proteases)FDA Link 04/2010
1	Metalloproteases (Metalloproteinases)IBA 04/2010
1	MetallochaperonesIBA 07/2008
1	alpha-SynucleinIBA 06/2008
1	Codon (Codons)IBA 12/2006
1	AsparagineIBA 03/2003

Therapy/Procedure

1	Therapeutics 01/2018
1	Hematopoietic Stem Cell Transplantation 01/2018